Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.66 |
| ▸ | AXL | P30530 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 8/20 | 0.54 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | APP | P05067 | 7/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1639031 | 0.81 | GFER (0.63) | GFERAXLALDH1A1MAPTKDM4E | |
| SCHEMBL7700068 | 0.79 | GFER (0.61) | GFERAXLALDH1A1MAPTKDM4E | |
| SCHEMBL21017367 | 0.79 | HTT (0.61) | APPDYRK1AHTTGAAL3MBTL1 | |
| SCHEMBL2615303 | 0.79 | SMN1; SMN2 (0.61) | GFERAXLALDH1A1MAPTKDM4E | |
| SCHEMBL12844692 | 0.79 | GFER (0.61) | GFERAXLALDH1A1MAPTKDM4E | |
| SCHEMBL25165513 | 0.79 | RAB9A (0.61) | GFERAXLALDH1A1MAPTKDM4E | |
| SCHEMBL7005689 | 0.79 | GFER (0.61) | GFERAXLALDH1A1MAPTKDM4E | |
| SCHEMBL2615304 | 0.79 | SMN1; SMN2 (0.61) | GFERAXLALDH1A1MAPTKDM4E | |
| SCHEMBL369984 | 0.79 | GFER (0.61) | GFERAXLALDH1A1MAPTKDM4E | |
| SCHEMBL9717710 | 0.79 | SMN1; SMN2 (0.61) | GFERAXLALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0588183-A1 | Fluoro benzothiazolyloxyacetamide | BAYER AG (DE) | 1994-03-23 | — | — | EP | claimed |
| US-5442074-A | Sulfonyl containing fluorobenzothiazole as chemical intermediate | BAYER AKTIENGESELLSCHAFT (DE) | 1995-08-15 | — | — | US | disclosed |
| US-5356864-A | New herbicidal fluorobenzothiazolyloxyacetamides | BAYER AKTIENGESELLSCHAFT (DE) | 1994-10-18 | — | — | US | disclosed |
| EP-0588183-A1 | Fluoro benzothiazolyloxyacetamide | BAYER AG (DE) | 1994-03-23 | — | — | EP | disclosed |