Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.61 |
| ▸ | AXL | P30530 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 8/20 | 0.51 |
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | APP | P05067 | 5/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29764160 | 1.00 | GFER (0.61) | GFERAXLKMT2AALDH1A1MAPT | |
| SCHEMBL1747926 | 0.84 | DYRK1A (0.49) | GFERAXLKMT2AALDH1A1MAPT | |
| SCHEMBL334252 | 0.81 | NPC1 (0.61) | KMT2AALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL9255622 | 0.79 | GFER (0.66) | GFERAXLKMT2AALDH1A1MAPT | |
| SCHEMBL1639031 | 0.78 | GFER (0.63) | GFERAXLKMT2AALDH1A1MAPT | |
| SCHEMBL2615304 | 0.76 | SMN1; SMN2 (0.61) | GFERAXLKMT2AALDH1A1MAPT | |
| SCHEMBL2615303 | 0.76 | SMN1; SMN2 (0.61) | GFERAXLKMT2AALDH1A1MAPT | |
| SCHEMBL7005689 | 0.76 | GFER (0.61) | GFERAXLKMT2AALDH1A1MAPT | |
| SCHEMBL7222746 | 0.76 | GFER (0.61) | GFERAXLKMT2AALDH1A1MAPT | |
| SCHEMBL12844692 | 0.76 | GFER (0.61) | GFERAXLKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 292 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1087903-A | Fluoro benzothiazole oxygen yl acetamide | BAYER AG (DE) | 1994-06-15 | — | — | CN | claimed |
| EP-0588183-A1 | Fluoro benzothiazolyloxyacetamide | BAYER AG (DE) | 1994-03-23 | — | — | EP | claimed |
| US-12378254-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2025-08-05 | — | — | US | disclosed |
| EP-4081524-B1 | SUBSTITUTED HETEROARYL COMPOUNDS USEFUL AS T CELL ACTIVATORS | BRISTOL MYERS SQUIBB CO (US) | 2025-01-29 | — | — | EP | disclosed |
| US-20250011293-A1 | LEUKOTRIENE SYNTHESIS INHIBITORS | NAEGIS PHARMACEUTICALS INC. (CA) | 2025-01-09 | — | — | US | disclosed |
| CN-119059967-A | Diaryl amine compound with affinity with Tau protein, and preparation method and application thereof | 北京师范大学 | 2024-12-03 | — | — | CN | disclosed |
| US-12145927-B2 | Inhibitors of indoleamine 2,3-dioxygenase and methods of their use | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-11-19 | — | — | US | disclosed |
| US-11976052-B2 | Leukotriene synthesis inhibitors | NAEGIS PHARMACEUTICALS INC. (CA) | 2024-05-07 | — | — | US | disclosed |
| US-20240109901-A1 | DISUBSTITUTED OCTAHYDROPYRROLO[3,4-C]PYRROLES AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-04-04 | — | — | US | disclosed |
| EP-4061818-B1 | MACROCYCLIC PEPTIDES AS PD-L1 INHIBITORS AND IMMUNOMODULATORS FOR THE TREATMENT OF CANCER AND INFECTIOUS DISEASES | BRISTOL MYERS SQUIBB CO (US) | 2023-12-06 | — | — | EP | disclosed |
| EP-3458447-B1 | PIPERAZINYL METHANONE NAAA INHIBITORS | UNIV CALIFORNIA (US) | 2023-11-29 | — | — | EP | disclosed |
| EP-0588183-A1 | Fluoro benzothiazolyloxyacetamide | BAYER AG (DE) | 1994-03-23 | — | — | EP | disclosed |
| CN-1068822-A | The benzothiazole derivant that replaces, its preparation and as herbicide applications | SCHER ING AG (DE) | 1993-02-10 | — | — | CN | disclosed |
| US-5169855-A | PIPERIDINE ETHER DERIVATIVES AS PSYCHOTROPIC DRUGS OR PLANT FUNGICIDES | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-12-08 | — | — | US | disclosed |
| EP-0449187-A2 | Piperidin ether derivatives as psychotropic drugs or plant fungicides | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-10-02 | — | — | EP | disclosed |
| EP-0444764-A1 | Process and intermediates for the preparation of substituted 1-benzothiazolyl-3,4-dimethyl-3-pyrrolin-2,5(1H)-diones | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-09-04 | — | — | EP | disclosed |
| EP-0373461-A2 | Benzazoles | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1990-06-20 | — | — | EP | disclosed |
| EP-0039440-B1 | MEDICINES CONTAINING SUBSTITUTED BENZOTHIAZOL-2-(3H)-ONES | Dr. Karl Thomae GmbH (DE) | 1983-06-22 | — | — | EP | disclosed |
| US-4353919-A | Analgesic and antipyretic pharmaceutical compositions containing a benzothiazol-2(3H)-one | DR. KARL THOMAE GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-10-12 | — | — | US | disclosed |
| EP-0039440-A1 | Medicines containing substituted benzothiazol-2-(3H)-ones | Dr. Karl Thomae GmbH (DE) | 1981-11-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12145927-B2 | Inhibitors of indoleamine 2,3-dioxygenase and methods of their use | IDO1, IDO2, INMT | GFER 2600/4885AXL 3158/4885KMT2A 533/4885 |
| US-20240109901-A1 | DISUBSTITUTED OCTAHYDROPYRROLO[3,4-C]PYRROLES AS OREXIN RECEPTOR MODULATORS | HCRTR2, HCRTR1, OXTR | GFER 2687/4885AXL 582/4885KMT2A 1722/4885 |
| US-12378254-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | HCRTR2, HCRTR1, OXTR | GFER 2687/4885AXL 582/4885KMT2A 1722/4885 |
| US-11976052-B2 | Leukotriene synthesis inhibitors | LTC4S, LTB4R2, LTA4H | GFER 449/4885AXL 4428/4885KMT2A 4046/4885 |
| US-20250011293-A1 | LEUKOTRIENE SYNTHESIS INHIBITORS | LTC4S, LTB4R2, LTA4H | GFER 449/4885AXL 4428/4885KMT2A 4046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.