Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PTGFR | P43088 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9455333 | 0.82 | NPSR1 (0.33) | SLC6A4SLC6A2SLC6A3NPSR1TSHR | |
| SCHEMBL8846207 | 0.81 | AKR1C3 (0.33) | — | |
| SCHEMBL9190928 | 0.81 | AKR1C3 (0.33) | — | |
| SCHEMBL8967700 | 0.81 | SLC6A4 (0.37) | SLC6A4SLC6A2SLC6A3KDM4ETDP1 | |
| SCHEMBL9580540 | 0.80 | NOS2 (0.33) | SLC6A4SLC6A2SLC6A3ALDH1A1 | |
| SCHEMBL9580494 | 0.75 | SLC6A2 (0.30) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL8967739 | 0.74 | NPSR1 (0.36) | SLC6A4SLC6A2SLC6A3NPSR1TSHR | |
| SCHEMBL9191960 | 0.69 | NPC1 (0.39) | NPSR1KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL9580493 | 0.68 | HPGD (0.41) | SLC6A4SLC6A2SLC6A3TSHRKDM4E | |
| SCHEMBL9580479 | 0.68 | PYGL (0.32) | SLC6A4SLC6A2SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459149-A | Penta-2,4-dienamides and use as pesticides | ROUSSEL UCLAF (FR) | 1995-10-17 | — | — | US | disclosed |