Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.43 |
| ▸ | NPC1 | O15118 | 8/20 | 0.43 |
| ▸ | RAB9A | P51151 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | ATP4A | P20648 | 2/20 | 0.40 |
| ▸ | ATP4B | P51164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6484619 | 0.76 | PDE10A (0.60) | MAPTALDH1A1MEN1KMT2APDE10A | |
| SCHEMBL2787396 | 0.71 | FBP1 (0.43) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL12735602 | 0.68 | PDGFRB (0.50) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL11771726 | 0.68 | KDM4E (0.50) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL11048397 | 0.67 | PDGFRB (0.47) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL6598963 | 0.67 | PDGFRB (0.49) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL1853061 | 0.67 | NPC1 (0.53) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL8508679 | 0.67 | PDGFRB (0.49) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL27914891 | 0.67 | PDGFRB (0.49) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL650259 | 0.66 | NPC1 (0.51) | MAPTNPC1RAB9AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995029897-A1 | METHOD OF USING (H+/K+) ATPase INHIBITORS AS ANTIVIRAL AGENTS | G.D. SEARLE & CO. (US) | 1995-11-09 | — | — | WO | claimed |
| WO-1995029897-A1 | METHOD OF USING (H+/K+) ATPase INHIBITORS AS ANTIVIRAL AGENTS | G.D. SEARLE & CO. (US) | 1995-11-09 | — | — | WO | disclosed |