SCHEMBL2787396

SCHEMBL2787396

COc1ccc(Sc2cccs2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 2/20 0.43
PTGIR P43119 2/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
TP53 P04637 1/20 0.41
HAO1 Q9UJM8 1/20 0.40
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
POLB P06746 2/20 0.40
ALDH1A1 P00352 6/20 0.39
CYP1A2 P05177 2/20 0.39
MAPT P10636 2/20 0.39
CYP1A1 P04798 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2787935 0.81 HPGD (0.42) FBP1PTGIRRAB9ATP53KMT2A
SCHEMBL2784678 0.81 RAB9A (0.48) FBP1PTGIRNPC1RAB9ASMN1; SMN2
SCHEMBL2785817 0.79 FBP1 (0.48) FBP1NPC1RAB9ASMN1; SMN2TP53
SCHEMBL2786028 0.78 ALDH1A1 (0.49) CA12CA1CA2CA7CA9
SCHEMBL17079196 0.78 HSD17B10 (0.46) FBP1NPC1RAB9ASMN1; SMN2TP53
SCHEMBL2785886 0.78 RAB9A (0.46) FBP1CA12CA1CA2CA7
SCHEMBL2787901 0.77 MAPT (0.40) FBP1NPC1RAB9ASMN1; SMN2TP53
SCHEMBL588852 0.76 FBP1 (0.54) FBP1SMN1; SMN2KMT2AALDH1A1MAPT
SCHEMBL482369 0.75 CA1 (0.65) PTGIRCA12CA1CA2CA7
SCHEMBL2787500 0.75 NR1H2 (0.52) FBP1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2218715-B1 PHOTOACID GENERATOR AND PHOTOREACTIVE COMPOSITION SUMITOMO SEIKA CHEMICALS (JP) 2017-06-28 EP disclosed
CN-101925594-B Photoacid generators and photoreactive compositions SUMITOMO SEIKA CHEMICALS 2013-11-20 CN disclosed
US-8216768-B2 Photoacid generator and photoreactive composition SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2012-07-10 US disclosed
CN-101925594-A Photoacid generators and photoreactive compositions SUMITOMO SEIKA CHEMICALS 2010-12-22 CN disclosed
US-20100233621-A1 PHOTOACID GENERATOR AND PHOTOREACTIVE COMPOSITION SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 2010-09-16 US disclosed
EP-2218715-A1 PHOTOACID GENERATOR AND PHOTOREACTIVE COMPOSITION Sumitomo Seika Chemicals CO. LTD. (JP) 2010-08-18 EP disclosed
US-5158971-A Antiallergens, antiinflammatory agents LILLY INDUSTRIES LIMITED (GB) 1992-10-27 US disclosed
EP-0459748-A2 Thien-2-yl methylurea derivatives as leukotriene inhibitors LILLY INDUSTRIES LIMITED (GB) 1991-12-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100233621-A1 PHOTOACID GENERATOR AND PHOTOREACTIVE COMPOSITION ARSA, SULT1A1, CYBA FBP1 3147/4885PTGIR 3169/4885CA12 2049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.