Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT2 | P31751 | 10/20 | 0.49 |
| ▸ | AKT1 | P31749 | 9/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257888 | 0.96 | AKT2 (0.51) | AKT2AKT1HRH3 | |
| SCHEMBL9254431 | 0.89 | AKT2 (0.44) | AKT2AKT1HRH3SYK | |
| SCHEMBL9248511 | 0.85 | HRH3 (0.42) | HRH3SYK | |
| SCHEMBL9251212 | 0.85 | HRH3 (0.42) | HRH3 | |
| SCHEMBL9259539 | 0.84 | AKT2 (0.47) | AKT2AKT1HRH3 | |
| SCHEMBL9250844 | 0.82 | HRH3 (0.42) | HRH3 | |
| SCHEMBL9257434 | 0.81 | NPC1 (0.42) | HRH3 | |
| SCHEMBL9259602 | 0.81 | HRH3 (0.40) | HRH3SYK | |
| SCHEMBL9255567 | 0.81 | HRH3 (0.40) | HRH3SYK | |
| SCHEMBL9259034 | 0.81 | NPC1 (0.42) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| US-5401768-A | Prostaglandin derivative, antiulcer, hypotensive, anticoagulant | TORAY INDUSTRIES, INC. (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |