Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | CA9 | Q16790 | 3/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CDK4 | P11802 | 2/20 | 0.42 |
| ▸ | CCND1 | P24385 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259395 | 0.82 | CA12 (0.41) | CA12CA2CA9CA1 | |
| SCHEMBL9257826 | 0.81 | FEN1 (0.55) | KDM4ECA12CA2CA9CA1 | |
| SCHEMBL9255535 | 0.81 | ALDH1A1 (0.51) | KDM4EHSD17B10PKMGAAKMT2A | |
| SCHEMBL9262316 | 0.79 | KIF11 (0.42) | KDM4ECA9HSD17B10PKMGAA | |
| SCHEMBL9259975 | 0.79 | CA9 (0.43) | CA12CA9MAPT | |
| SCHEMBL9257797 | 0.78 | CA12 (0.58) | CA12CA9KMT2AMAPTNPSR1 | |
| SCHEMBL9261018 | 0.78 | ALK (0.39) | — | |
| SCHEMBL9264418 | 0.78 | FEN1 (0.58) | SMN1; SMN2 | |
| SCHEMBL9255519 | 0.78 | CCNB2 (0.36) | KDM4ECA12CA9HSD17B10PKM | |
| SCHEMBL9257755 | 0.77 | ADORA3 (0.54) | KDM4ECA12CA9GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995019346-A1 | QUINAZOLINE-2,4-DIONES | SANDOZ LTD. (CH) | 1995-07-20 | — | — | WO | claimed |
| WO-1995019346-A1 | QUINAZOLINE-2,4-DIONES | SANDOZ LTD. (CH) | 1995-07-20 | — | — | WO | disclosed |