Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.54 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | JAK2 | O60674 | 2/20 | 0.47 |
| ▸ | JAK1 | P23458 | 2/20 | 0.47 |
| ▸ | TYK2 | P29597 | 2/20 | 0.47 |
| ▸ | JAK3 | P52333 | 2/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | EGLN1 | Q9GZT9 | 5/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.43 |
| ▸ | PDE6D | O43924 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9254502 | 0.99 | ITGB3 (0.53) | ITGB3ITGA2BPPARGJAK2JAK1 | |
| SCHEMBL9255552 | 0.93 | RHEB (0.48) | ITGB3ITGA2BPPARGJAK2JAK1 | |
| SCHEMBL9251467 | 0.93 | JAK2 (0.49) | ITGB3ITGA2BPPARGJAK2JAK1 | |
| SCHEMBL9251963 | 0.91 | ITGB3 (0.46) | ITGB3ITGA2BPPARGJAK2JAK1 | |
| Bromide SCHEMBL9251333 | 0.91 | ITGB3 (0.45) | ITGB3ITGA2BPPARGJAK2JAK1 | |
| Hydrochloric Acid SCHEMBL9253317 | 0.90 | PTGER4 (0.47) | ITGB3ITGA2BPPARGJAK2JAK1 | |
| SCHEMBL9253344 | 0.89 | JAK2 (0.52) | ITGB3ITGA2BJAK2JAK1TYK2 | |
| SCHEMBL9249301 | 0.89 | PTGER4 (0.47) | ITGB3ITGA2BJAK2JAK1TYK2 | |
| SCHEMBL9251618 | 0.89 | JAK2 (0.51) | ITGB3ITGA2BJAK2JAK1TYK2 | |
| SCHEMBL9255433 | 0.89 | JAK2 (0.50) | ITGB3ITGA2BJAK2JAK1TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5434150-A | Anticoagulants, cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1995-07-18 | — | — | US | claimed |
| EP-0531883-A1 | Condensed 5-membered ring heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-03-17 | — | — | EP | claimed |