Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 7/20 | 0.44 |
| ▸ | THRB | P10828 | 7/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251073 | 0.96 | HSD17B10 (0.50) | HSD17B10L3MBTL1THRATHRBGAA | |
| SCHEMBL9259979 | 0.91 | KMT2A (0.44) | HSD17B10L3MBTL1THRATHRBGAA | |
| SCHEMBL9257183 | 0.86 | THRA (0.49) | THRATHRBRARB | |
| SCHEMBL8161551 | 0.85 | MMP12 (0.47) | HSD17B10L3MBTL1THRBGAAKMT2A | |
| SCHEMBL8159086 | 0.85 | MMP12 (0.48) | HSD17B10L3MBTL1THRATHRBRARB | |
| SCHEMBL9259438 | 0.85 | THRB (0.47) | L3MBTL1THRATHRBKMT2A | |
| SCHEMBL9252643 | 0.84 | RARB (0.56) | RARBKMT2AMEN1ALDH1A1RARA | |
| SCHEMBL9260132 | 0.84 | ESR1 (0.54) | HSD17B10ALDH1A1MAPT | |
| SCHEMBL9261332 | 0.83 | THRA (0.46) | THRATHRBRARB | |
| SCHEMBL8164558 | 0.82 | MMP12 (0.53) | HSD17B10GAARARBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5385693-A | Having rapid response and low phase transition temperature | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-01-31 | — | — | US | disclosed |
| EP-0357372-B1 | Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element | SUMITOMO CHEMICAL CO (JP) | 1994-11-17 | — | — | EP | disclosed |
| US-5264151-A | Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-11-23 | — | — | US | disclosed |
| US-5124070-A | High speed response | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-06-23 | — | — | US | disclosed |
| EP-0357372-A2 | Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-03-07 | — | — | EP | disclosed |