SCHEMBL9256367

SCHEMBL9256367

CCc1cccc(COC=O)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOD1 P00441 1/20 0.40
MGLL Q99685 1/20 0.40
TP53 P04637 1/20 0.38
BCL2 P10415 1/20 0.38
MAOA P21397 2/20 0.37
MAOB P27338 2/20 0.37
PTPN1 P18031 1/20 0.36
IDO1 P14902 3/20 0.36
KDM1A O60341 1/20 0.36
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35
MAPK1 P28482 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
NPC1 O15118 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11394076 0.90 MAOB (0.39) MAOAMAOBPTPN1IDO1AGXT
SCHEMBL9258159 0.85 CHRM2 (0.37) MAOAMAOB
SCHEMBL9249594 0.82 XIAP (0.43)
SCHEMBL15723548 0.81 MRGPRX4 (0.45) TP53MAOAMAOBPTPN1SMN1; SMN2
SCHEMBL1822742 0.81 IDO1 (0.58) MAOAMAOBIDO1
SCHEMBL147464 0.79 ALDH1A1 (0.43) SOD1MGLLTP53ALDH1A1CYP2A6
SCHEMBL6666977 0.79 CALM1 (0.44) MAOAMAOBPTPN1TSHRAGXT
SCHEMBL6667797 0.79 CHRM2 (0.55) SOD1TP53MAOAMAOBIDO1
SCHEMBL7359415 0.78 ENPP2 (0.50) ALDH1A1KDM4ECYP1A2MAPK1SMN1; SMN2
SCHEMBL1828440 0.78 IDO1 (0.61) MAOBIDO1AGXT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5470851-A Antihistamine, anticoagulants SANKYO COMPANY, LIMITED (JP) 1995-11-28 US disclosed
EP-0463873-A1 Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use Sankyo Company Limited (JP) 1992-01-02 EP disclosed