SCHEMBL9256410

SCHEMBL9256410

CN(c1ccccc1)c1cc[c]c2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CHKA P35790 7/20 0.38
EGFR P00533 3/20 0.37
PDE5A O76074 2/20 0.35
CHKB Q9Y259 1/20 0.33
MEN1 O00255 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
PDGFRB P09619 2/20 0.31
KDR P35968 2/20 0.31
TOP2A P11388 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL296148 0.81 KDM4E (0.33)
SCHEMBL249747 0.81 CHEK1 (0.44) CHKAMEN1HTTKMT2A
SCHEMBL9252140 0.78 APAF1 (0.38) EGFR
SCHEMBL27695382 0.75
SCHEMBL9255244 0.73 NR3C2 (0.36) HTT
SCHEMBL9830323 0.73 ELANE (0.32)
SCHEMBL297213 0.73 AR (0.33)
SCHEMBL297631 0.71 KDM4E (0.31)
SCHEMBL293332 0.70 GAA (0.56) KMT2A
SCHEMBL279082 0.69 CHKA (0.41) CHKAEGFRPDE5ACHKBMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5395969-A Charge transport or control agents; photoconductors; electrographic toners ZENECA LIMITED (GB) 1995-03-07 US disclosed
US-5279655-A Triarylmethane dye or lake pigment FUJICOPIAN CO., LTD. (JP) 1994-01-18 US disclosed
EP-0502200-A1 PRINTER INK COMPOSITION AND PRINTING MEDIUM PREPARED THEREFROM FUJICOPIAN CO., LTD. (JP) 1992-09-09 EP disclosed
EP-0304613-B1 BENZOPYRAN DERIVATIVES BASF Aktiengesellschaft (DE) 1991-06-26 EP disclosed
US-4958021-A PRESSURE AND HEAT SENSITIVE RECORDING MATERIALS BASF AKTIENGESELLSCHAFT (DE) 1990-09-18 US disclosed
EP-0304613-A1 Benzopyran derivatives BASF Aktiengesellschaft (DE) 1989-03-01 EP disclosed