SCHEMBL279082

SCHEMBL279082

CN(c1ccccc1)c1ccc(N(c2ccccc2)c2ccccc2)c2ccccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHKA P35790 7/20 0.41
EGFR P00533 1/20 0.41
CHEK1 O14757 1/20 0.39
NEK2 P51955 1/20 0.39
LIMK1 P53667 1/20 0.39
DYRK1A Q13627 1/20 0.39
CLK4 Q9HAZ1 1/20 0.39
PDE5A O76074 2/20 0.39
EP300 Q09472 1/20 0.38
KAT2B Q92831 1/20 0.38
KAT8 Q9H7Z6 1/20 0.38
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL279633 0.94 CHKA (0.41) CHKAEGFRCHEK1NEK2LIMK1
SCHEMBL14465392 0.91 CHKA (0.46) CHKAEGFRPDE5ACHKB
SCHEMBL13990081 0.88 CHKA (0.44) CHKAEGFRPDE5AKDM4EALDH1A1
SCHEMBL10110902 0.87 ALDH1A1 (0.44) CHEK1NEK2LIMK1DYRK1ACLK4
SCHEMBL14465689 0.86 CHKA (0.45) CHKAEGFRPDE5ACHKB
SCHEMBL14465391 0.84 CHKA (0.44) CHKACHEK1NEK2LIMK1DYRK1A
SCHEMBL12888139 0.84 ALDH1A1 (0.42) CHEK1NEK2LIMK1DYRK1ACLK4
SCHEMBL12262924 0.83 CYP1A2 (0.45) CHKAEGFRCHEK1NEK2LIMK1
SCHEMBL15250087 0.83 CHKA (0.40) CHKAEGFRPDE5AMEN1KMT2A
SCHEMBL12047767 0.83 SIGMAR1 (0.50) CHKAPDE5AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2444470-B1 LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, AND ELECTRONIC APPLIANCE SEMICONDUCTOR ENERGY LAB CO LTD (JP) 2016-10-26 EP disclosed
US-20160197278-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-07-07 US disclosed
US-20160197278-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-07-07 US disclosed
US-9287511-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-03-15 US disclosed
US-9174927-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-03 US disclosed
US-9174927-B2 Stilbene derivatives, light-emitting element, display device, and electronic device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-03 US disclosed
US-9048436-B2 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-02 US disclosed
US-9048436-B2 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-06-02 US disclosed
US-20140299822-A1 Oxadiazole Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Oxadiazole Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-10-09 US disclosed
US-20140299822-A1 Oxadiazole Derivative, and Light Emitting Element, Light Emitting Device, and Electronic Device Using the Oxadiazole Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-10-09 US disclosed
US-20080103315-A1 Anthracene Derivative, and Light Emitting Element, Light Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-05-01 US disclosed
US-20080103315-A1 Anthracene Derivative, and Light Emitting Element, Light Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-05-01 US disclosed
US-20080091030-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-04-17 US disclosed
US-20080091030-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2008-04-17 US disclosed
US-20080017853-A1 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-01-24 US disclosed
US-20080017853-A1 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-01-24 US disclosed
WO-2007125934-A1 ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-11-08 WO disclosed
WO-2007074893-A1 OXADIAZOLE DERIVATIVE, AND LIGHT EMITTING ELEMENT, LIGHT EMITTING DEVICE, AND ELECTRONIC DEVICE USING THE OXADIAZOLE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-07-05 WO disclosed
US-20070149784-A1 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-06-28 US disclosed
US-20070149784-A1 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2007-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080091030-A1 Stilbene Derivatives, Light-Emitting Element, Display Device, and Electronic Device NR2E3, NR0B2, NR0B1 CHKA 4157/4885EGFR 2086/4885CHEK1 4173/4885
US-20070149784-A1 Oxadiazole derivative, and light emitting element, light emitting device, and electronic device using the oxadiazole derivative OXA1L, ADRA1D, CRY1 CHKA 4135/4885EGFR 3052/4885CHEK1 1625/4885
US-20080017853-A1 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative XPOT, XPO1, XPO7 CHKA 4365/4885EGFR 1859/4885CHEK1 2873/4885
US-20160197278-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative XPOT, XPO1, XPO7 CHKA 4365/4885EGFR 1859/4885CHEK1 2873/4885
US-20080103315-A1 Anthracene Derivative, and Light Emitting Element, Light Emitting Device, Electronic Device Using Anthracene Derivative AMY1A, CYP1A1, CRY1 CHKA 4014/4885EGFR 2545/4885CHEK1 2685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.