Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9252140 | 0.83 | APAF1 (0.38) | NR3C2TSHRALDH1A1NPC1GLA | |
| SCHEMBL296148 | 0.76 | KDM4E (0.33) | ALDH1A1CYP2C19MAPT | |
| SCHEMBL284744 | 0.73 | SIGMAR1 (0.44) | NR3C2TSHRHDAC1HDAC8HDAC6 | |
| SCHEMBL9256410 | 0.73 | CHKA (0.38) | HTT | |
| SCHEMBL918512 | 0.71 | NR3C2 (0.56) | NR3C2TSHRHDAC1HDAC8HDAC6 | |
| SCHEMBL9446230 | 0.69 | NR3C2 (0.59) | NR3C2TSHRHDAC1HDAC8HDAC6 | |
| Bromide SCHEMBL4613403 | 0.69 | NR3C2 (0.55) | NR3C2TSHRHDAC1HDAC8HDAC6 | |
| SCHEMBL5843435 | 0.69 | NR3C2 (0.47) | NR3C2TSHRHDAC1HDAC8HDAC6 | |
| SCHEMBL249747 | 0.69 | CHEK1 (0.44) | TSHRALDH1A1HTTSMN1; SMN2CYP2C19 | |
| SCHEMBL297213 | 0.68 | AR (0.33) | TSHRALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5395969-A | Charge transport or control agents; photoconductors; electrographic toners | ZENECA LIMITED (GB) | 1995-03-07 | — | — | US | disclosed |