Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9262771 | 0.84 | MAPT (0.51) | NPC1MAPTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL9262816 | 0.83 | ALDH1A1 (0.41) | NPC1MAPTRAB9APOLBTAS1R3 | |
| SCHEMBL9251832 | 0.83 | HDAC6 (0.49) | NPC1MAPTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL9255150 | 0.80 | GAA (0.46) | NPC1MAPTRAB9ALMNAGAA | |
| SCHEMBL9260289 | 0.73 | LMNA (0.42) | MAPTSMN1; SMN2LMNAGAATP53 | |
| Hydrochloric Acid SCHEMBL23420320 | 0.71 | TP53 (0.46) | NPC1MAPTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL12709534 | 0.71 | MAOB (0.52) | NPC1MAPTRAB9AMAPK1KMT2A | |
| SCHEMBL30686654 | 0.71 | TP53 (0.46) | NPC1MAPTRAB9ASMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL29695992 | 0.71 | TP53 (0.46) | NPC1MAPTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL3726748 | 0.71 | TP53 (0.46) | NPC1MAPTRAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432195-A | Anticholesterol | NIPPON SHINYAKU COMPANY LIMITED (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0601181-A1 | BENZOFURAN DERIVATIVE AND PHARMACEUTICAL COMPOSITION | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1994-06-15 | — | — | EP | disclosed |