Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Phosphine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphine SCHEMBL30340926 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL3980396 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL2677630 | 0.82 | — | — | |
| Phosphine SCHEMBL3987102 | 0.67 | — | — | |
| Phosphine SCHEMBL2784977 | 0.67 | — | — | |
| Phosphine SCHEMBL3147000 | 0.67 | — | — | |
| Phosphine SCHEMBL11749972 | 0.67 | — | — | |
| Phosphine SCHEMBL11857502 | 0.67 | — | — | |
| Phosphine SCHEMBL3672901 | 0.67 | — | — | |
| Phosphine SCHEMBL1943937 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432194-A | Antiallergens, antinflammatory agents | ABBOTT LABORATORIES (US) | 1995-07-11 | — | — | US | disclosed |