Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641255 | 0.91 | KDM4E (0.43) | ADRB2ADRB1ADRB3NPC1MAPT | |
| SCHEMBL9253512 | 0.88 | ALDH1A1 (0.49) | NPC1MAPTRAB9ASMN1; SMN2MAOB | |
| SCHEMBL7619158 | 0.86 | NPC1 (0.52) | ADRB2ADRB1ADRB3NPC1MAPT | |
| SCHEMBL8026374 | 0.86 | NPC1 (0.52) | ADRB2ADRB1ADRB3NPC1MAPT | |
| SCHEMBL9282589 | 0.85 | ADRB2 (0.47) | ADRB2ADRB1ADRB3NPC1MAPT | |
| SCHEMBL23386424 | 0.83 | MAPT (0.49) | ADRB2ADRB1ADRB3NPC1MAPT | |
| SCHEMBL8825580 | 0.82 | KMT2A (0.51) | ADRB2ADRB1ADRB3NPC1MAPT | |
| SCHEMBL9640410 | 0.82 | KDM4E (0.43) | ADRB2ADRB1ADRB3NPC1MAPT | |
| SCHEMBL10332262 | 0.82 | MAPT (0.47) | ADRB2ADRB1ADRB3NPC1MAPT | |
| SCHEMBL19601251 | 0.81 | ADRB2 (0.49) | ADRB2ADRB1ADRB3NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3271258-A | — | — | None | — | — | JP | disclosed |
| US-5454974-A | Halobenzene liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1995-10-03 | — | — | US | disclosed |
| US-5302317-A | Halobenzene liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1994-04-12 | — | — | US | disclosed |
| US-5230826-A | HALOBENZENE LIQUID CRYSTALS | HOFFMANN-LA ROCHE INC. (US) | 1993-07-27 | — | — | US | disclosed |
| JP-H03271258-A | DIFLUOROPHENYL ALLYLOXYBENZOATE | ASAHI DENKA KOGYO KK | 1991-12-03 | — | — | JP | disclosed |
| US-5013477-A | Alkenylbicyclohexane liquid crystals | HOFFMANN-LA ROCHE INC. (US) | 1991-05-07 | — | — | US | disclosed |