Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641255 | 0.92 | KDM4E (0.43) | KDM4ENPC1MAPTRAB9APOLB | |
| SCHEMBL14767086 | 0.85 | MAPT (0.43) | KDM4ENPC1MAPTRAB9APOLB | |
| SCHEMBL12741912 | 0.83 | ALDH1A1 (0.39) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL8026374 | 0.83 | NPC1 (0.52) | NPC1MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL7619158 | 0.83 | NPC1 (0.52) | NPC1MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL9256549 | 0.82 | ADRB2 (0.45) | NPC1MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL9282589 | 0.82 | ADRB2 (0.47) | NPC1MAPTRAB9APOLBSMN1; SMN2 | |
| SCHEMBL8026485 | 0.81 | ALDH1A1 (0.43) | KDM4ENPC1MAPTRAB9APOLB | |
| SCHEMBL12822874 | 0.80 | KDM4E (0.38) | KDM4EMAPTADRB2ADRB1ADRB3 | |
| SCHEMBL10340005 | 0.80 | KDM4E (0.50) | KDM4ENPC1MAPTRAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0357702-B1 | FLUORINATED OLIGOPHENYL DERIVATIVES | MERCK PATENT GmbH (DE) | 1992-08-12 | — | — | EP | disclosed |
| EP-0357702-A1 | FLUORINATED OLIGOPHENYL DERIVATIVES. | MERCK PATENT GMBH (DE) | 1990-03-14 | — | — | EP | disclosed |
| WO-1989006678-A1 | FLUORINATED OLIGOPHENYL DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-07-27 | — | — | WO | disclosed |