Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CCR9 | P51686 | 2/20 | 0.31 |
| ▸ | VDR | P11473 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | AKT2 | P31751 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257107 | 0.85 | F2 (0.37) | HDAC1HRH3HPGDTSHRHSD17B10 | |
| SCHEMBL9254257 | 0.80 | HDAC1 (0.33) | HDAC1HRH3HPGDTSHRHSD17B10 | |
| SCHEMBL9259034 | 0.78 | NPC1 (0.42) | HRH3HPGDTSHRHSD17B10 | |
| SCHEMBL9257434 | 0.78 | NPC1 (0.42) | HRH3HPGDTSHRHSD17B10 | |
| Hydrochloric Acid SCHEMBL9256062 | 0.77 | NPC1 (0.41) | HRH3HPGDTSHRHSD17B10 | |
| SCHEMBL9253103 | 0.77 | ALOX5 (0.38) | HPGD | |
| SCHEMBL9256582 | 0.74 | HRH3 (0.36) | HDAC1HRH3HPGDTSHRHSD17B10 | |
| SCHEMBL9248511 | 0.73 | HRH3 (0.42) | HDAC1HRH3HPGDTSHRHSD17B10 | |
| SCHEMBL9251212 | 0.73 | HRH3 (0.42) | HDAC1HRH3HPGDTSHRHSD17B10 | |
| SCHEMBL9256832 | 0.72 | ACVR1 (0.41) | HRH3HPGDTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |