Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CD74 | P04233 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257107 | 0.90 | F2 (0.37) | HPGDGAAALDH1A1F2F10 | |
| SCHEMBL9255731 | 0.85 | ALDH1A1 (0.38) | HPGDKDM4EMEN1GAAKMT2A | |
| SCHEMBL9247338 | 0.85 | MAPT (0.38) | HPGDKDM4ETDP1ALDH1A1MAPT | |
| SCHEMBL9288922 | 0.84 | TDP1 (0.43) | ALOX5APPKDM4EMEN1KMT2A | |
| SCHEMBL9255106 | 0.84 | ALDH1A1 (0.36) | HPGDKDM4EMEN1GAAKMT2A | |
| SCHEMBL9254257 | 0.83 | HDAC1 (0.33) | HPGDKDM4EGAAALDH1A1F2 | |
| SCHEMBL9256887 | 0.81 | ALDH1A1 (0.37) | HPGDKDM4ETDP1ALDH1A1NAMPT | |
| SCHEMBL9253096 | 0.80 | TDP1 (0.40) | ALOX5APPHPGDKDM4EMEN1 | |
| SCHEMBL9256586 | 0.77 | HDAC1 (0.35) | HPGD | |
| SCHEMBL9257668 | 0.76 | KDM4E (0.36) | HPGDKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |