Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | CCKAR | P32238 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302596 | 0.84 | BDKRB1 (0.43) | CCKBRALDH1A1MAPT | |
| SCHEMBL9008657 | 0.84 | BDKRB1 (0.43) | CCKBRALDH1A1MAPT | |
| SCHEMBL9302606 | 0.84 | BDKRB1 (0.43) | CCKBRALDH1A1MAPT | |
| SCHEMBL9008655 | 0.84 | BDKRB1 (0.43) | CCKBRALDH1A1MAPT | |
| SCHEMBL9008654 | 0.84 | BDKRB1 (0.43) | CCKBRALDH1A1MAPT | |
| SCHEMBL9301875 | 0.84 | BDKRB1 (0.43) | CCKBRALDH1A1MAPT | |
| SCHEMBL9261341 | 0.79 | SENP1 (0.58) | CCKBRALDH1A1SENP1 | |
| SCHEMBL7591006 | 0.79 | SENP1 (0.58) | CCKBRALDH1A1SENP1 | |
| SCHEMBL9261337 | 0.79 | SENP1 (0.58) | CCKBRALDH1A1SENP1 | |
| SCHEMBL9302412 | 0.75 | BDKRB1 (0.45) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5451582-A | Cholecystokinins and gastrin receptor antagonists | MERCK SHARP & DOHME LTD. (GB) | 1995-09-19 | — | — | US | disclosed |