Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4363347 | 0.80 | ALDH1A1 (0.44) | HTTALDH1A1HPGDKDM4ERECQL | |
| SCHEMBL987234 | 0.77 | ALDH1A1 (0.42) | HTTALDH1A1HPGDKDM4ERECQL | |
| SCHEMBL1935518 | 0.77 | CACNA1G (0.42) | CACNA1GCACNA1BCACNA1CHTTALDH1A1 | |
| Water SCHEMBL21776630 | 0.76 | ALDH1A1 (0.41) | HTTALDH1A1HPGDKDM4ERECQL | |
| SCHEMBL7883597 | 0.76 | ALDH1A1 (0.41) | HTTALDH1A1HPGDKDM4ERECQL | |
| SCHEMBL7298547 | 0.75 | ALDH1A1 (0.40) | HTTALDH1A1HPGDKDM4ERECQL | |
| SCHEMBL7878657 | 0.75 | ALDH1A1 (0.40) | HTTALDH1A1HPGDKDM4ERECQL | |
| SCHEMBL8861128 | 0.74 | ALDH1A1 (0.40) | HTTALDH1A1HPGDKDM4ERECQL | |
| SCHEMBL11947892 | 0.72 | CACNA1G (0.44) | CACNA1GCACNA1BCACNA1CHTTALDH1A1 | |
| SCHEMBL8244423 | 0.72 | ALDH1A1 (0.48) | HTTALDH1A1HPGDKDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459148-A | Cardiovascular disorders | SANKYO COMPANY, LIMITED (JP) | 1995-10-17 | — | — | US | disclosed |