SCHEMBL9256751

SCHEMBL9256751

C=CCSc1ccnnn1

nearest known ligand 0.36

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
L3MBTL1 Q9Y468 3/20 0.35
SMN1; SMN2 Q16637 4/20 0.35
PKM P14618 1/20 0.35
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
HPGD P15428 3/20 0.32
NPC1 O15118 3/20 0.31
RAB9A P51151 3/20 0.31
TP53 P04637 2/20 0.31
ALOX15 P16050 1/20 0.31
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
TSHR P16473 1/20 0.31
MAPT P10636 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5792102 0.77 SMN1; SMN2 (0.41) ALDH1A1L3MBTL1SMN1; SMN2PKMKMT2A
SCHEMBL9015917 0.74 EHMT2 (0.35)
SCHEMBL11014040 0.74
SCHEMBL726340 0.74
SCHEMBL10700739 0.71 ALDH1A1 (0.36) ALDH1A1L3MBTL1SMN1; SMN2KMT2AMEN1
SCHEMBL10848409 0.70
SCHEMBL7328306 0.70
SCHEMBL27885318 0.69
SCHEMBL6939168 0.69 HPGD (0.37) ALDH1A1L3MBTL1SMN1; SMN2PKMKMT2A
SCHEMBL11193955 0.69 PKM (0.42) ALDH1A1L3MBTL1SMN1; SMN2PKMKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461434-B1 Substituted triazine-capped polyphenylene ethers GEN ELECTRIC (US) 1995-09-20 EP claimed
EP-0462410-B1 Copolymer-containing compositions from substituted triazine-capped polyphenylene ethers GEN ELECTRIC (US) 1995-08-23 EP claimed
JP-4226153-A None JP disclosed
JP-4226130-A None JP disclosed
JP-H04226153-A COPOLYMER-CONTAINING COMPOSITION FROM SUBSTITUTED TRIAZINE-CAPPED POLYPHENYLENE ETHER GENERAL ELECTRIC CO <GE> 1992-08-14 JP disclosed
JP-H04226130-A SUBSTITUTED TRIAZINE CAPPED POLYPHENYLENE ETHERS GENERAL ELECTRIC CO <GE> 1992-08-14 JP disclosed
US-4659359-A 2-chloro-4,6-diamino-s-triazines as algicides CIBA-GEIGY CORPORATION (US) 1987-04-21 US disclosed
EP-0032357-B1 USE OF 2-CHLORO-4,6-DIAMINO-S-TRIAZINES AS ALGICIDES CIBA-GEIGY AG (CH) 1983-09-21 EP disclosed
EP-0032357-A2 Use of 2-chloro-4,6-diamino-s-triazines as algicides CIBA-GEIGY AG (CH) 1981-07-22 EP disclosed