Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 3/20 | 0.36 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261314 | 0.87 | PTGIR (0.42) | CHRM3PTGIRKMT2AMEN1MAPT | |
| SCHEMBL9260639 | 0.83 | ALDH1A1 (0.42) | MMP9ALDH1A1CYP3A4CYP2C19KMT2A | |
| SCHEMBL9260511 | 0.83 | ALDH1A1 (0.44) | MMP9PRKCAPRKCDALDH1A1CYP1A2 | |
| SCHEMBL9265911 | 0.81 | F2 (0.39) | MMP9PRKCAPRKCDALDH1A1SLC15A1 | |
| SCHEMBL9258866 | 0.81 | HTT (0.39) | CYP2C19KMT2ACCR5 | |
| SCHEMBL9261682 | 0.80 | MMP9 (0.37) | MMP9PRKCAPRKCDALDH1A1KMT2A | |
| SCHEMBL9256762 | 0.80 | CHRM3 (0.39) | CHRM3ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9262109 | 0.80 | MEN1 (0.42) | ALDH1A1KMT2AMEN1CCR5 | |
| SCHEMBL9257349 | 0.79 | LMNA (0.42) | MMP9PRKCAPRKCDALDH1A1SLC15A1 | |
| SCHEMBL9257263 | 0.77 | KMT2A (0.46) | CHRM3CYP2D6CYP2C9KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |