Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16674537 | 0.81 | CXCR2 (0.46) | MAPTCXCR2KEAP1KMT2ACXCR1 | |
| SCHEMBL7224966 | 0.78 | ADRA1D (0.51) | ADRA1DADRA1AADRA1BMAPTCXCR2 | |
| SCHEMBL474163 | 0.76 | ADRA1D (0.48) | ADRA1DADRA1AADRA1BMAPTKEAP1 | |
| SCHEMBL15265666 | 0.75 | MAPT (0.48) | ADRA1DADRA1AADRA1BMAPTGAA | |
| SCHEMBL10987377 | 0.75 | MT-CO2 (0.49) | ADRA1DADRA1AADRA1BMAPTCXCR2 | |
| SCHEMBL12411070 | 0.74 | AKR1C3 (0.46) | CXCR2KMT2ATP53MEN1ALDH1A1 | |
| SCHEMBL1899962 | 0.74 | KMT2A (0.54) | ADRA1AMAPTGAAKMT2AHPGD | |
| SCHEMBL31552440 | 0.74 | AKR1C3 (0.46) | CXCR2KMT2ATP53MEN1ALDH1A1 | |
| SCHEMBL10837558 | 0.74 | ADRA1D (0.53) | ADRA1DADRA1AADRA1BMAPTKMT2A | |
| SCHEMBL960115 | 0.73 | CTSD (0.50) | ADRA1DADRA1AADRA1BMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672032-A1 | NOVEL PHENYLETHYL AND PHENYLPROPYLAMINES | Astra Aktiebolag (SE) | 1995-09-20 | — | — | EP | disclosed |