Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.81 |
| ▸ | HTR2C | P28335 | 1/20 | 0.81 |
| ▸ | HTR2B | P41595 | 1/20 | 0.81 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.54 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26391938 | 0.90 | HTR2A (1.00) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL6344464 | 0.86 | HTR2A (0.73) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL6154035 | 0.85 | HTR2A (0.69) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL6154064 | 0.83 | GAA (0.70) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL10963541 | 0.83 | KCNH2 (0.73) | HTR2AHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL228242 | 0.83 | HTR2A (0.76) | HTR2AHTR2CHTR2BSLC18A3 | |
| SCHEMBL6209404 | 0.83 | HTR2A (0.66) | HTR2AHTR2CHTR2BKMT2A | |
| SCHEMBL9246613 | 0.82 | HTR2A (0.59) | HTR2AHTR2CHTR2B | |
| SCHEMBL4500124 | 0.81 | ACHE (0.77) | — | |
| SCHEMBL9253050 | 0.80 | SMN1; SMN2 (0.64) | HTR2AHTR2CHTR2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5441967-A | Treating cerebral edema; anticholinesterase or brain function-improving agent | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-08-15 | — | — | US | disclosed |
| CN-1024548-C | Cyclic amine compounds and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1994-05-18 | — | — | CN | disclosed |
| US-5294625-A | 1-benzyl,4-((4-dialkylaminophenyl)carbonyl)piperidines | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-03-15 | — | — | US | disclosed |
| EP-0378207-B1 | CYCLIC AMINE COMPOUNDS AND THEIR USE | Takeda Chemical Industries, Ltd. (JP) | 1993-09-22 | — | — | EP | disclosed |
| US-5177087-A | Cerebral edema, cholinesterase inhibitor | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| CN-1053231-A | Cyclic amine compound and uses thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1991-07-24 | — | — | CN | disclosed |
| EP-0378207-A1 | Cyclic amine compounds and their use | Takeda Chemical Industries, Ltd. (JP) | 1990-07-18 | — | — | EP | disclosed |