Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261324 | 0.90 | ALDH1A1 (0.51) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9256867 | 0.84 | KDM4E (0.45) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9253426 | 0.83 | KDM4E (0.55) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9588769 | 0.82 | ALDH1A1 (0.72) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9255871 | 0.81 | KDM4E (0.51) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9258929 | 0.81 | KDM4E (0.50) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9249471 | 0.77 | KDM4E (0.47) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL6578990 | 0.76 | ALDH1A1 (0.64) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9252356 | 0.75 | KDM4E (0.47) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9760582 | 0.74 | KDM4E (0.61) | ALDH1A1KDM4ESMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382572-A | Viricides | SCHERING CORPORATION (US) | 1995-01-17 | — | — | US | disclosed |
| EP-0547145-A1 | ANTIVIRAL 2(1H)-QUINOLINONE COMPOUNDS | SCHERING CORPORATION (US) | 1993-06-23 | — | — | EP | disclosed |
| WO-1992004326-A1 | ANTIVIRAL COMPOUNDS | SCHERING CORPORATION (US) | 1992-03-19 | — | — | WO | disclosed |