Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9252678 | 0.88 | ELANE (0.52) | KDM4EALDH1A1MAPTMITFLMNA | |
| SCHEMBL9257528 | 0.88 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTMITFLMNA | |
| SCHEMBL9257319 | 0.85 | EDNRB (0.46) | KDM4EALDH1A1MAPTMITFLMNA | |
| SCHEMBL9256830 | 0.83 | ALDH1A1 (0.61) | KDM4EALDH1A1MAPTMITFLMNA | |
| SCHEMBL9258929 | 0.81 | KDM4E (0.50) | KDM4EALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL9256867 | 0.80 | KDM4E (0.45) | KDM4EALDH1A1MAPTMITFLMNA | |
| SCHEMBL9255291 | 0.80 | KMT2A (0.46) | KDM4EALDH1A1MAPTMITFLMNA | |
| SCHEMBL9252356 | 0.78 | KDM4E (0.47) | KDM4EALDH1A1MAPTMITFLMNA | |
| SCHEMBL9261324 | 0.73 | ALDH1A1 (0.51) | KDM4EALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL9257233 | 0.73 | KDM4E (0.53) | KDM4EALDH1A1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382572-A | Viricides | SCHERING CORPORATION (US) | 1995-01-17 | — | — | US | disclosed |
| EP-0547145-A1 | ANTIVIRAL 2(1H)-QUINOLINONE COMPOUNDS | SCHERING CORPORATION (US) | 1993-06-23 | — | — | EP | disclosed |
| WO-1992004326-A1 | ANTIVIRAL COMPOUNDS | SCHERING CORPORATION (US) | 1992-03-19 | — | — | WO | disclosed |