Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.58 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.58 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PHGDH | O43175 | 1/20 | 0.46 |
| ▸ | MASP2 | O00187 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258406 | 0.87 | ITGB3 (0.55) | ITGB3ITGA2BCSNK2A1MAPTMEN1 | |
| SCHEMBL9253949 | 0.76 | ITGB3 (0.52) | ITGB3ITGA2BMAPTMEN1RAB9A | |
| Hydrochloric Acid SCHEMBL8824115 | 0.75 | ITGB3 (0.98) | ITGB3ITGA2BRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL8824031 | 0.75 | ITGB3 (0.98) | ITGB3ITGA2BRAB9ANPC1 | |
| Trifluoroacetic Acid SCHEMBL3174446 | 0.75 | LMNA (0.57) | MAPTMEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL7287931 | 0.75 | ITGB3 (0.55) | ITGB3ITGA2BCSNK2A1MAPTMEN1 | |
| SCHEMBL8107316 | 0.74 | ITGB3 (1.00) | ITGB3ITGA2BRAB9ANPC1 | |
| SCHEMBL4590880 | 0.74 | KMT2A (0.59) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL8173189 | 0.72 | ALDH1A1 (0.65) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL7539560 | 0.72 | NPC1 (0.53) | ITGB3ITGA2BMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |