Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | GLS | O94925 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | MMP3 | P08254 | 3/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9251061 | 0.88 | CYP11B1 (0.52) | CYP11B1CYP11B2EGLN1BLMMAPT | |
| SCHEMBL8879099 | 0.86 | HTT (0.48) | CYP11B1CYP11B2GLSEGLN1BLM | |
| SCHEMBL3628694 | 0.80 | CYP11B1 (0.56) | CYP11B1CYP11B2EGLN1MAPTPOLB | |
| SCHEMBL9254531 | 0.80 | TMPRSS15 (0.43) | MAPTHPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3628690 | 0.79 | CYP11B1 (0.55) | CYP11B1CYP11B2EGLN1MAPTPOLB | |
| SCHEMBL9257116 | 0.78 | CSNK2A2 (0.42) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL1338556 | 0.75 | CYP11B1 (0.60) | CYP11B1CYP11B2MAPTPOLBALDH1A1 | |
| SCHEMBL9251931 | 0.75 | CYP11B1 (0.52) | CYP11B1CYP11B2EGLN1MAPTPOLB | |
| SCHEMBL161099 | 0.75 | GLS (0.46) | GLSBLMMAPTKDM4EHDAC1 | |
| SCHEMBL8879927 | 0.75 | SLC22A12 (0.46) | GLSEGLN1BLMMMP2MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |