Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 11/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9252726 | 0.85 | TMPRSS15 (0.38) | ITGB3ITGA2BPRSS1TMPRSS15NQO2 | |
| SCHEMBL9253132 | 0.81 | ITGB3 (0.51) | ITGB3ITGA2BPRSS1TMPRSS15NQO2 | |
| SCHEMBL9256974 | 0.81 | ITGB3 (0.51) | ITGB3ITGA2BPRSS1TMPRSS15NQO2 | |
| SCHEMBL28401740 | 0.81 | CHRM1 (0.49) | — | |
| SCHEMBL9258365 | 0.79 | NQO2 (0.38) | ITGB3ITGA2BPRSS1TMPRSS15NQO2 | |
| SCHEMBL1695555 | 0.78 | WDR5 (0.40) | WDR5PRSS1NQO2 | |
| SCHEMBL9255412 | 0.78 | ITGB3 (0.43) | ITGB3ITGA2BWDR5PRSS1TMPRSS15 | |
| SCHEMBL9254490 | 0.77 | F10 (0.38) | ITGB3ITGA2B | |
| SCHEMBL9255778 | 0.77 | ITGB3 (0.37) | ITGB3ITGA2BPRSS1TMPRSS15NQO2 | |
| SCHEMBL9252117 | 0.74 | NR1H4 (0.63) | ITGB3ITGA2BWDR5PRSS1TMPRSS15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |