Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 8/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.43 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.40 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.39 |
| ▸ | ITGAM | P11215 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9255915 | 0.89 | ITGB3 (0.44) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| SCHEMBL9254303 | 0.88 | TMPRSS15 (0.43) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| SCHEMBL9256974 | 0.83 | ITGB3 (0.51) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| SCHEMBL9253132 | 0.83 | ITGB3 (0.51) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| SCHEMBL9253478 | 0.81 | KLK1 (0.38) | ITGB3ITGA2BPRSS1F2PRSS2 | |
| SCHEMBL9258365 | 0.78 | NQO2 (0.38) | ITGB3ITGA2BPRSS1TMPRSS15 | |
| SCHEMBL9254922 | 0.77 | GRK6 (0.42) | ITGB3ITGA2B | |
| SCHEMBL9254458 | 0.77 | ITGB3 (0.52) | ITGB3ITGA2BPRSS1 | |
| SCHEMBL9259804 | 0.76 | MMP2 (0.44) | — | |
| SCHEMBL9254490 | 0.76 | F10 (0.38) | ITGB3ITGA2BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |