Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.41 |
| ▸ | RARA | P10276 | 2/20 | 0.32 |
| ▸ | RARB | P10826 | 2/20 | 0.32 |
| ▸ | RARG | P13631 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.31 |
| ▸ | GOT1 | P17174 | 1/20 | 0.31 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258875 | 1.00 | PLA2G4A (0.41) | PLA2G4ARARARARBRARGS1PR1 | |
| SCHEMBL9258569 | 0.92 | PLA2G4A (0.39) | PLA2G4AHDAC11 | |
| SCHEMBL8796839 | 0.91 | PLA2G4A (0.42) | PLA2G4ARARARARBRARGS1PR1 | |
| SCHEMBL9259400 | 0.88 | PLA2G4A (0.41) | PLA2G4AS1PR1 | |
| SCHEMBL8795834 | 0.81 | PLA2G4A (0.40) | PLA2G4ARARARARBRARG | |
| SCHEMBL8795840 | 0.81 | PLA2G4A (0.40) | PLA2G4ARARARARBRARG | |
| SCHEMBL8796070 | 0.79 | PLA2G4A (0.42) | PLA2G4ARARARARBRARGS1PR1 | |
| SCHEMBL8794991 | 0.78 | PLA2G4A (0.42) | PLA2G4ARARARARBRARGMEN1 | |
| SCHEMBL8795002 | 0.78 | PLA2G4A (0.42) | PLA2G4ARARARARBRARGMEN1 | |
| SCHEMBL8765769 | 0.78 | S1PR1 (0.37) | PLA2G4ARARARARBRARGS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5436369-A | Alicyclic phospholipase A2 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-07-25 | — | — | US | disclosed |