Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257313 | 0.92 | PLA2G4A (0.41) | PLA2G4AHDAC11 | |
| SCHEMBL9258875 | 0.92 | PLA2G4A (0.41) | PLA2G4AHDAC11 | |
| SCHEMBL8795840 | 0.90 | PLA2G4A (0.40) | PLA2G4AALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL8795834 | 0.90 | PLA2G4A (0.40) | PLA2G4AALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9259400 | 0.89 | PLA2G4A (0.41) | PLA2G4AALDH1A1 | |
| SCHEMBL8796839 | 0.83 | PLA2G4A (0.42) | PLA2G4A | |
| SCHEMBL8796070 | 0.81 | PLA2G4A (0.42) | PLA2G4AALDH1A1 | |
| SCHEMBL8796507 | 0.81 | PLA2G4A (0.39) | PLA2G4A | |
| SCHEMBL8796517 | 0.81 | PLA2G4A (0.39) | PLA2G4A | |
| SCHEMBL8795002 | 0.79 | PLA2G4A (0.42) | PLA2G4AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5436369-A | Alicyclic phospholipase A2 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-07-25 | — | — | US | disclosed |