Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 7/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9257320 | 1.00 | SLC6A3 (1.00) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL9260012 | 0.85 | SLC6A3 (0.76) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL9257271 | 0.85 | SLC6A3 (1.00) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL9257274 | 0.85 | SLC6A3 (1.00) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7355992 | 0.85 | SLC6A3 (0.76) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7355995 | 0.85 | SLC6A3 (0.76) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL9260009 | 0.85 | SLC6A3 (0.76) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7457834 | 0.82 | SLC6A3 (0.70) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7457839 | 0.82 | SLC6A3 (0.70) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7457828 | 0.82 | SLC6A3 (0.70) | SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5391744-A | Enhanced analgesic and vasoconstrictive properties | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1995-02-21 | — | — | US | disclosed |
| US-5268480-A | Containing an aromatic ester | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 1993-12-07 | — | — | US | disclosed |