Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3682302 | 0.82 | KDM4E (0.59) | TSHRLMNAHSD17B10ALDH1A1KMT2A | |
| SCHEMBL21034615 | 0.81 | SLC6A3 (0.56) | SLC6A3TSHRLMNAL3MBTL1SLC6A4 | |
| Methyl 2-Methoxybenzoate SCHEMBL196037 | 0.77 | TSHR (0.69) | SLC6A3TSHRLMNAL3MBTL1SLC6A4 | |
| SCHEMBL2441955 | 0.77 | SLC6A3 (0.65) | SLC6A3TSHRLMNAL3MBTL1SLC6A4 | |
| Methyl 2-Methoxybenzoate SCHEMBL29702077 | 0.77 | TSHR (0.69) | SLC6A3TSHRLMNAL3MBTL1SLC6A4 | |
| SCHEMBL3820895 | 0.77 | NPC1 (0.37) | SLC6A3TSHRLMNAL3MBTL1HSD17B10 | |
| SCHEMBL1162463 | 0.77 | KDM4E (0.69) | SLC6A3TSHRLMNAL3MBTL1SLC6A4 | |
| SCHEMBL30941613 | 0.77 | KDM4E (0.69) | SLC6A3TSHRLMNAL3MBTL1SLC6A4 | |
| Methyl 2-Methoxybenzoate SCHEMBL30744939 | 0.76 | MAPT (0.67) | SLC6A3TSHRLMNAL3MBTL1SLC6A4 | |
| SCHEMBL28432969 | 0.76 | KMT2A (0.63) | SLC6A3TSHRLMNAL3MBTL1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382572-A | Viricides | SCHERING CORPORATION (US) | 1995-01-17 | — | — | US | disclosed |
| EP-0547145-A1 | ANTIVIRAL 2(1H)-QUINOLINONE COMPOUNDS | SCHERING CORPORATION (US) | 1993-06-23 | — | — | EP | disclosed |
| US-5190956-A | Certain N-substituted 3-oximino-2,4-dioxoquinolin-2,4-(1H)diones useful for treating viral infections | SCHERING CORPORATION (US) | 1993-03-02 | — | — | US | disclosed |
| US-5179107-A | Herpes | SCHERING CORPORATION (US) | 1993-01-12 | — | — | US | disclosed |
| WO-1992004326-A1 | ANTIVIRAL COMPOUNDS | SCHERING CORPORATION (US) | 1992-03-19 | — | — | WO | disclosed |