Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 11/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259585 | 0.85 | BRS3 (0.45) | BRS3HDAC3HDAC1HDAC2ALDH1A1 | |
| SCHEMBL8556962 | 0.75 | HDAC3 (0.45) | HDAC3HDAC1HDAC2MEN1ALDH1A1 | |
| SCHEMBL16568954 | 0.75 | KMT2A (0.54) | HDAC3HDAC1HDAC2ALDH1A1GAA | |
| SCHEMBL30785575 | 0.73 | GAA (0.55) | HDAC3HDAC1HDAC2GAAKMT2A | |
| SCHEMBL9367046 | 0.73 | BRS3 (0.73) | BRS3MEN1KMT2A | |
| SCHEMBL9367824 | 0.73 | BRS3 (0.73) | BRS3MEN1KMT2A | |
| SCHEMBL20160888 | 0.72 | GSK3B (0.60) | HDAC3HDAC1HDAC2MEN1GAA | |
| Hydrochloric Acid SCHEMBL18208874 | 0.71 | GSK3B (0.59) | HDAC3HDAC1HDAC2MEN1GAA | |
| SCHEMBL9370827 | 0.71 | BRS3 (0.77) | BRS3ALDH1A1GAALMNATSHR | |
| SCHEMBL9366479 | 0.71 | BRS3 (0.77) | BRS3ALDH1A1GAALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459138-A | Dysfunctions of glutamatergic neurotransmission associated with learning and memory | ADIR ET COMPAGNIE (FR) | 1995-10-17 | — | — | US | disclosed |