Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | METAP2 | P50579 | 1/20 | 0.51 |
| ▸ | METAP1 | P53582 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10753491 | 0.92 | HSP90AA1 (0.60) | HSP90AA1LMNAL3MBTL1METAP2METAP1 | |
| SCHEMBL11217622 | 0.87 | HSP90AA1 (0.52) | HSP90AA1LMNAL3MBTL1METAP2METAP1 | |
| SCHEMBL10751843 | 0.87 | HSP90AA1 (0.63) | HSP90AA1LMNAL3MBTL1METAP2METAP1 | |
| SCHEMBL5250058 | 0.83 | FAAH (0.64) | HSP90AA1LMNAPOLBKDM4EMAPT | |
| SCHEMBL11084416 | 0.80 | HSP90AA1 (0.55) | HSP90AA1LMNAL3MBTL1METAP2METAP1 | |
| SCHEMBL4411378 | 0.80 | HSP90AA1 (0.68) | HSP90AA1KDM4EMAPTGAAMEN1 | |
| SCHEMBL795857 | 0.79 | HSP90AA1 (0.68) | HSP90AA1LMNAL3MBTL1METAP2METAP1 | |
| SCHEMBL9813597 | 0.79 | NCEH1 (0.72) | NCEH1KDM4EGAA | |
| SCHEMBL3453951 | 0.78 | HSP90AA1 (0.62) | HSP90AA1LMNAL3MBTL1METAP2METAP1 | |
| SCHEMBL10752030 | 0.78 | LMNA (0.55) | HSP90AA1LMNAL3MBTL1METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5438056-A | Anticholesterol agents | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-08-01 | — | — | US | disclosed |