Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | METAP2 | P50579 | 1/20 | 0.60 |
| ▸ | METAP1 | P53582 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | PGR | P06401 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28131091 | 0.84 | HSP90AA1 (0.68) | HSP90AA1L3MBTL1LMNAMETAP2METAP1 | |
| SCHEMBL6525865 | 0.84 | HSP90AA1 (0.63) | HSP90AA1L3MBTL1LMNAMETAP2METAP1 | |
| SCHEMBL10751843 | 0.84 | HSP90AA1 (0.63) | HSP90AA1L3MBTL1LMNAMETAP2METAP1 | |
| SCHEMBL7364217 | 0.83 | L3MBTL1 (0.62) | HSP90AA1L3MBTL1LMNAMETAP2METAP1 | |
| SCHEMBL250301 | 0.82 | LMNA (0.65) | HSP90AA1L3MBTL1LMNAMETAP2METAP1 | |
| SCHEMBL28459061 | 0.82 | LMNA (0.69) | HSP90AA1L3MBTL1LMNAMETAP2METAP1 | |
| SCHEMBL10753491 | 0.81 | HSP90AA1 (0.60) | HSP90AA1L3MBTL1LMNAMETAP2METAP1 | |
| SCHEMBL10385035 | 0.81 | LMNA (0.72) | HSP90AA1L3MBTL1LMNAMETAP2METAP1 | |
| Hydrochloric Acid SCHEMBL2563239 | 0.81 | LMNA (0.63) | HSP90AA1L3MBTL1LMNAMETAP2METAP1 | |
| Butanedione SCHEMBL5530736 | 0.81 | LMNA (0.63) | HSP90AA1L3MBTL1LMNAMETAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | claimed |
| US-5124455-A | Enzyme inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-23 | — | — | US | claimed |
| EP-0255984-B1 | PROCESS FOR PREPARING 2-METHYL 2-(METHYLTHIO) PROPIONALDEHYDE 0-(METHYLCARBAMOYL) OXIME AS A WATER-WET CAKE | RHONE POULENC NEDERLAND B.V. (NL) | 1991-10-16 | — | — | EP | claimed |
| US-4710508-A | ANALGESICS | WARNER-LAMBERT COMPANY (US) | 1987-12-01 | — | — | US | claimed |
| US-4060627-A | Substituted tetrahydroiminobenzo(b)thien-4-ylureas as novel growth promoting compounds for animals | AMERICAN CYANAMID COMPANY (US) | 1977-11-29 | — | — | US | claimed |
| US-20140162906-A1 | Pesticide Biomarker | NAGY JON OWEN (US) | 2014-06-12 | — | — | US | disclosed |
| US-20130089530-A1 | METHODS AND COMPOSITIONS FOR TREATING PARASITIC WORM INFECTIONS IN A MAMMAL | MICROBES, INC. (US) | 2013-04-11 | — | — | US | disclosed |
| WO-2012037352-A2 | METHODS AND COMPOSITIONS FOR REDUCING PATHOGENS IN SOIL AND IMPROVING PLANT GROWTH | MICROBES, INC. (US) | 2012-03-22 | — | — | WO | disclosed |
| US-20110166043-A1 | BIOMARKER DETECTION-2 | ATERIS TECHNOLOGIES, LLC | 2011-07-07 | — | — | US | disclosed |
| US-20100041077-A1 | PESTICIDE BIOMARKER | ATERIS TECHNOLOGIES, LLC | 2010-02-18 | — | — | US | disclosed |
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | disclosed |
| EP-1035770-A4 | USE OF FATTY ALCOHOL CARBONATES AS SOLVENTS IN AGRICULTURAL FORMULATIONS | COGNIS CORP (US) | 2002-07-24 | — | — | EP | disclosed |
| EP-0255984-A1 | Process for preparing 2-methyl 2-(methylthio) propionaldehyde 0-(methylcarbamoyl) oxime as a water-wet cake | RHONE POULENC NEDERLAND B.V. (NL) | 1988-02-17 | — | — | EP | disclosed |
| US-4710508-A | ANALGESICS | WARNER-LAMBERT COMPANY (US) | 1987-12-01 | — | — | US | disclosed |
| US-4640927-A | PESTICIDES, NEMATOCIDES, MITICIDES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1987-02-03 | — | — | US | disclosed |
| EP-0158496-A2 | Substituted oxime carbamates | UNIROYAL, INC. (US) | 1985-10-16 | — | — | EP | disclosed |
| EP-0155862-A1 | Process for the preparation of carbamic acid esters derivatives | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1985-09-25 | — | — | EP | disclosed |
| US-4208409-A | N-[(phosphinyl or phosphinothioyl)amino]thio-methylcarbamates and pesticidal methods | THE UPJOHN COMPANY (US) | 1980-06-17 | — | — | US | disclosed |
| US-4201733-A | PESTICIDES | THE UPJOHN COMPANY (US) | 1980-05-06 | — | — | US | disclosed |
| US-4108991-A | INSECTICIDES, MITICIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1978-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166043-A1 | BIOMARKER DETECTION-2 | CPB2, NAALAD2, PRSS2 | HSP90AA1 3904/4885L3MBTL1 1532/4885LMNA 4505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.