Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | HPGD | P15428 | 7/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MPI | P34949 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995853 | 0.78 | GBA1 (0.68) | GBA1MAPTHSD17B10MAPK1TSHR | |
| SCHEMBL6993105 | 0.70 | KDM4E (0.73) | GBA1MAPTHSD17B10MAPK1TSHR | |
| SCHEMBL6996694 | 0.70 | GBA1 (0.57) | GBA1MAPTHSD17B10MAPK1TSHR | |
| SCHEMBL8361989 | 0.69 | KDM4E (0.56) | GBA1MAPTHSD17B10MAPK1TSHR | |
| SCHEMBL12723861 | 0.69 | ACHE (0.57) | GBA1HSD17B10MAPK1TSHRKDM4E | |
| SCHEMBL13021649 | 0.68 | GBA1 (0.54) | GBA1MAPTHSD17B10MAPK1TSHR | |
| SCHEMBL9319149 | 0.68 | KDM4E (0.55) | GBA1MAPTHSD17B10MAPK1TSHR | |
| SCHEMBL10519698 | 0.68 | CA12 (0.41) | GBA1MAPTHSD17B10MAPK1TSHR | |
| SCHEMBL6999092 | 0.67 | PON1 (0.64) | GBA1MAPTHSD17B10MAPK1TSHR | |
| SCHEMBL29528063 | 0.67 | SHBG (0.67) | GBA1MAPTHSD17B10MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382572-A | Viricides | SCHERING CORPORATION (US) | 1995-01-17 | — | — | US | disclosed |
| EP-0547145-A1 | ANTIVIRAL 2(1H)-QUINOLINONE COMPOUNDS | SCHERING CORPORATION (US) | 1993-06-23 | — | — | EP | disclosed |
| WO-1992004326-A1 | ANTIVIRAL COMPOUNDS | SCHERING CORPORATION (US) | 1992-03-19 | — | — | WO | disclosed |