Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 5/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | MPI | P34949 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10939957 | 0.83 | KDM4E (0.67) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL7912397 | 0.82 | ADORA3 (0.59) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL9318447 | 0.79 | ALDH1A1 (0.45) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL12987096 | 0.76 | KDM4E (0.54) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL12986404 | 0.76 | KDM4E (0.54) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL6995853 | 0.75 | GBA1 (0.68) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL3052874 | 0.75 | KDM4E (0.68) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL8123765 | 0.75 | ADORA3 (0.60) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL10995103 | 0.74 | KDM4E (0.62) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL12986819 | 0.73 | KDM4E (0.72) | KDM4EALDH1A1MAPTHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371220-A | Bicyclo-heterocyclic intermediates for cephalosporin compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-12-06 | — | — | US | disclosed |