Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 11/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 11/20 | 0.45 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | F10 | P00742 | 3/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258249 | 0.86 | ITGB3 (0.51) | S1PR1S1PR3F2F10PRSS1 | |
| SCHEMBL9258660 | 0.83 | F2 (0.44) | F2F10PRSS1ST14ITGB3 | |
| Hydrochloric Acid SCHEMBL9254391 | 0.79 | ST14 (0.54) | F2F10PRSS1ST14ITGB3 | |
| SCHEMBL9257819 | 0.79 | NPC1 (0.50) | F2ST14ITGB3ITGA2B | |
| SCHEMBL9257084 | 0.78 | F2 (0.41) | F2F10PRSS1ST14ITGB3 | |
| SCHEMBL9568559 | 0.78 | F2 (0.41) | F2F10PRSS1ST14ITGB3 | |
| SCHEMBL9254388 | 0.78 | F2 (0.43) | F2F10PRSS1ST14 | |
| Hydrochloric Acid SCHEMBL9254684 | 0.78 | NPC1 (0.49) | F2ST14ITGB3ITGA2B | |
| SCHEMBL9250170 | 0.78 | NQO2 (0.61) | F2F10PRSS1 | |
| SCHEMBL9257434 | 0.77 | NPC1 (0.42) | F2F10PRSS1ST14ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |