Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 4/20 | 0.44 |
| ▸ | F10 | P00742 | 4/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.44 |
| ▸ | NQO2 | P16083 | 3/20 | 0.43 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14018791 | 0.88 | HSD17B10 (0.47) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL9250754 | 0.87 | KMT2A (0.49) | MAPTSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL9250170 | 0.85 | NQO2 (0.61) | F2F10PRSS1NQO2TMPRSS15 | |
| SCHEMBL9257683 | 0.85 | ITGB3 (0.56) | F2F10PRSS1NQO2ST14 | |
| Hydrochloric Acid SCHEMBL9254391 | 0.84 | ST14 (0.54) | F2F10PRSS1ST14ITGB3 | |
| SCHEMBL9253124 | 0.84 | F2 (0.45) | F2F10PRSS1ST14TMPRSS15 | |
| SCHEMBL9257765 | 0.83 | S1PR1 (0.45) | F2F10PRSS1ST14ITGB3 | |
| SCHEMBL9253071 | 0.80 | NQO2 (0.56) | F2F10PRSS1NQO2ST14 | |
| SCHEMBL9251931 | 0.80 | CYP11B1 (0.52) | GSK3AGSK3BMAPTSMN1; SMN2KDM4E | |
| SCHEMBL9254388 | 0.78 | F2 (0.43) | F2F10PRSS1NQO2ST14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |