Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.35 |
| ▸ | HNF4A | P41235 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.34 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5261044 | 0.85 | LMNA (0.44) | LMNAMEN1KMT2APOLB | |
| SCHEMBL9782120 | 0.78 | LMNA (0.41) | CA12CA1CA2CA9CA14 | |
| SCHEMBL9266699 | 0.78 | MAPT (0.39) | LMNAMEN1KMT2AIP6K1MAOA | |
| SCHEMBL9266806 | 0.78 | MAPT (0.39) | LMNAMEN1KMT2AIP6K1MAOA | |
| SCHEMBL18748184 | 0.77 | CALM1 (0.38) | PLA2G10PLA2G2ACALM1MEN1KMT2A | |
| SCHEMBL18748183 | 0.75 | KDM4E (0.37) | LMNAMAOAMAOB | |
| SCHEMBL1375987 | 0.71 | BACE1 (0.44) | MEN1KMT2A | |
| SCHEMBL9269316 | 0.70 | MAOA (0.40) | LMNAMEN1KMT2AMAOAMAOB | |
| SCHEMBL9271143 | 0.69 | ACACB (0.38) | — | |
| SCHEMBL9264386 | 0.69 | GSTP1 (0.41) | MEN1KMT2AIP6K1IP6K3IP6K2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5464865-A | Enzyme inhibitors as antiinflammatory agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1995-11-07 | — | — | US | disclosed |