Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PRKDC | P78527 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24988962 | 0.82 | ERN1 (0.44) | KDM4ETSHRHSD17B10GLAMEN1 | |
| SCHEMBL17065833 | 0.72 | HPGD (0.44) | KDM4ETSHRHSD17B10GLAMEN1 | |
| SCHEMBL6002813 | 0.72 | PRKDC (0.46) | KDM4ETSHRMEN1KMT2APRKDC | |
| SCHEMBL9255869 | 0.70 | PRKDC (0.41) | KDM4ETSHRMEN1KMT2APRKDC | |
| Cyclohexane SCHEMBL27529217 | 0.69 | SIRT2 (0.46) | KDM4ETSHRHSD17B10MEN1KMT2A | |
| SCHEMBL56791 | 0.69 | ALDH1A1 (0.46) | KDM4ETSHRHSD17B10MEN1KMT2A | |
| SCHEMBL30020418 | 0.69 | ALDH1A1 (0.46) | KDM4ETSHRHSD17B10MEN1KMT2A | |
| SCHEMBL26200101 | 0.68 | ALDH1A1 (0.41) | KDM4ETSHRHSD17B10GLAMEN1 | |
| SCHEMBL5495489 | 0.67 | CYP2A6 (0.54) | KDM4ETSHRHSD17B10MAPK1ALDH1A1 | |
| SCHEMBL9466597 | 0.67 | ALDH1A1 (0.44) | KDM4ETSHRHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995002567-A1 | CATALYTIC ASYMMETRIC REDUCTION OF TRISUBSTITUTED OLEFINS AND ENAMINES | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1995-01-26 | — | — | WO | disclosed |