SCHEMBL9257845

SCHEMBL9257845

C=CC(O)NC(=S)C(N)=S

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7153578 0.84
SCHEMBL4069934 0.78 ALDH1A1 (0.30) ALDH1A1TSHR
SCHEMBL9576360 0.72
SCHEMBL170265 0.72
SCHEMBL11450914 0.68 TGFBR1 (0.39) ALDH1A1TSHR
SCHEMBL15167391 0.67 ALDH1A1 (0.32) ALDH1A1TSHR
Thiourea SCHEMBL27618620 0.66
SCHEMBL11016623 0.65
SCHEMBL9067167 0.65 LMNA (0.35) TSHR
SCHEMBL7802686 0.65 LMNA (0.35) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0434213-B1 Monosubstituted dithiooxamide compounds and their use MINNESOTA MINING & MFG (US) 1995-04-05 EP disclosed
US-5124308-A Reacts with transition metal salt for carbonless paper copying MINNESOTA MINING AND MANUFACTURING COMPANY 1992-06-23 US disclosed
US-5041654-A Transamination in wallach reaction; controlling temperature; reactant amine concentration MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-08-20 US disclosed
EP-0434213-A1 Monosubstituted dithiooxamide compounds and their use MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-06-26 EP disclosed
EP-0431783-A1 Preparation of monosubstituted dithiooxamide compounds MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-06-12 EP disclosed