Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | AVPR1B | P47901 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | SPNS2 | Q8IVW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259602 | 0.91 | HRH3 (0.40) | HRH3NPC1RAB9AAVPR1BHPGD | |
| SCHEMBL9251212 | 0.86 | HRH3 (0.42) | HRH3NPC1RAB9AAVPR1BHPGD | |
| SCHEMBL9248511 | 0.86 | HRH3 (0.42) | HRH3NPC1RAB9AAVPR1BHPGD | |
| SCHEMBL9257434 | 0.84 | NPC1 (0.42) | HRH3NPC1RAB9AHPGDTSHR | |
| SCHEMBL9259034 | 0.84 | NPC1 (0.42) | HRH3NPC1RAB9AHPGDTSHR | |
| Hydrochloric Acid SCHEMBL9256062 | 0.83 | NPC1 (0.41) | HRH3NPC1RAB9AHPGDTSHR | |
| SCHEMBL9250844 | 0.83 | HRH3 (0.42) | HRH3NPC1RAB9AMAPTAVPR1B | |
| SCHEMBL9257936 | 0.82 | HRH3 (0.39) | HRH3NPC1RAB9AAVPR1B | |
| SCHEMBL9255567 | 0.82 | HRH3 (0.40) | HRH3NPC1RAB9AMAPTAVPR1B | |
| SCHEMBL9259613 | 0.82 | HRH3 (0.40) | HRH3AVPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |