Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9253949 | 0.85 | ITGB3 (0.52) | MEN1ITGB3ITGA2BHDAC3HDAC4 | |
| SCHEMBL9257819 | 0.84 | NPC1 (0.50) | MEN1ITGB3ITGA2BRAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9254684 | 0.83 | NPC1 (0.49) | MEN1ITGB3ITGA2BRAB9AALDH1A1 | |
| SCHEMBL9253913 | 0.79 | PRMT1 (0.53) | L3MBTL1ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL9258406 | 0.79 | ITGB3 (0.55) | MEN1ITGB3ITGA2BRAB9AALDH1A1 | |
| SCHEMBL9248073 | 0.78 | GAA (0.43) | MEN1ITGB3ITGA2BALDH1A1LMNA | |
| SCHEMBL9254531 | 0.78 | TMPRSS15 (0.43) | ITGB3ITGA2BHDAC6MAPTSMN1; SMN2 | |
| SCHEMBL9251433 | 0.78 | ITGB3 (0.42) | MEN1ITGB3ITGA2BHDAC3HDAC4 | |
| SCHEMBL9252726 | 0.77 | TMPRSS15 (0.38) | ITGB3ITGA2BMAPTF2 | |
| SCHEMBL9254605 | 0.76 | ITGB3 (0.41) | ITGB3ITGA2BRAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463071-A | Tetrazole derivatives; useful for inhibiting undesirable cell aggregation | DR. KARL THOMAE GMBH (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0525629-A2 | 5-membered heterocycles, process for their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1993-02-03 | — | — | EP | disclosed |