Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 5/20 | 0.39 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.39 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9259942 | 0.84 | MAPT (0.39) | MEN1ALDH1A1KMT2A | |
| SCHEMBL9258279 | 0.84 | FAAH (0.41) | EPHX2FAAHSOAT2SOAT1CNR1 | |
| Methyl Alcohol SCHEMBL9267439 | 0.79 | ALDH1A1 (0.45) | CNR1ALDH1A1 | |
| SCHEMBL29035432 | 0.79 | EPHX2 (0.60) | EPHX2FAAHSOAT2SOAT1CNR1 | |
| SCHEMBL27674153 | 0.79 | EPHX2 (0.60) | EPHX2FAAHSOAT2SOAT1CNR1 | |
| SCHEMBL28906277 | 0.79 | EPHX2 (0.60) | EPHX2FAAHSOAT2SOAT1CNR1 | |
| SCHEMBL15537993 | 0.79 | EPHX2 (0.60) | EPHX2FAAHSOAT2SOAT1CNR1 | |
| SCHEMBL4623958 | 0.79 | EPHX2 (0.60) | EPHX2FAAHSOAT2SOAT1CNR1 | |
| SCHEMBL4623962 | 0.79 | EPHX2 (0.60) | EPHX2FAAHSOAT2SOAT1CNR1 | |
| SCHEMBL28192004 | 0.79 | EPHX2 (0.60) | EPHX2FAAHSOAT2SOAT1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |