Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PAM | P19021 | 2/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 2/20 | 0.37 |
| ▸ | TLR2 | O60603 | 2/20 | 0.37 |
| ▸ | SMPD2 | O60906 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ACER2 | Q5QJU3 | 1/20 | 0.37 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.36 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | UGCG | Q16739 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9258283 | 0.84 | EPHX2 (0.40) | ALDH1A1MEN1KMT2A | |
| Methyl Alcohol SCHEMBL9254484 | 0.81 | MAPT (0.45) | MAPTALDH1A1GABBR2GABBR1MEN1 | |
| SCHEMBL9263736 | 0.80 | MAPK1 (0.46) | MAPTALDH1A1GABBR2GABBR1MAPK1 | |
| SCHEMBL9259935 | 0.79 | PTGES (0.40) | TLR2MEN1KMT2ACYP1A2 | |
| SCHEMBL9257796 | 0.78 | MAPT (0.54) | MAPTALDH1A1GABBR2GABBR1MEN1 | |
| SCHEMBL7655013 | 0.73 | MAPT (0.55) | MAPTALDH1A1GABBR2GABBR1MEN1 | |
| SCHEMBL28380917 | 0.71 | MAPT (0.53) | MAPTPAMASAH1TLR2ALDH1A1 | |
| SCHEMBL28381562 | 0.71 | MAPT (0.53) | MAPTPAMASAH1TLR2ALDH1A1 | |
| SCHEMBL9328886 | 0.71 | GABBR2 (0.50) | MAPTASAH1ALDH1A1ACER2CERT1 | |
| SCHEMBL3242852 | 0.69 | GABBR2 (0.54) | MAPTGABBR2GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5393875-A | Hypotensive, cardiotonic and antiischemic agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | disclosed |