Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 17/20 | 0.32 |
| ▸ | CA2 | P00918 | 17/20 | 0.32 |
| ▸ | CA9 | Q16790 | 15/20 | 0.32 |
| ▸ | CA12 | O43570 | 5/20 | 0.31 |
| ▸ | CA7 | P43166 | 5/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.31 |
| ▸ | CA3 | P07451 | 4/20 | 0.31 |
| ▸ | CA4 | P22748 | 4/20 | 0.31 |
| ▸ | CA6 | P23280 | 4/20 | 0.31 |
| ▸ | CA5A | P35218 | 4/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10989515 | 0.76 | TSHR (0.56) | LMNAKDM4EUSP2ALDH1A1MMP9 | |
| SCHEMBL10223459 | 0.75 | KDM4E (0.37) | LMNAKDM4EUSP2ALDH1A1MMP9 | |
| SCHEMBL789504 | 0.73 | KDM4E (0.52) | LMNAKDM4EUSP2ALDH1A1MMP9 | |
| SCHEMBL20365425 | 0.73 | LMNA (0.38) | LMNA | |
| SCHEMBL313345 | 0.71 | USP2 (0.61) | LMNAKDM4EUSP2ALDH1A1MMP9 | |
| SCHEMBL9500520 | 0.71 | TSHR (0.61) | LMNAKDM4EUSP2ALDH1A1MMP9 | |
| Busulfan SCHEMBL4373 | 0.71 | TSHR (1.00) | LMNAKDM4EUSP2ALDH1A1MMP9 | |
| Busulfan SCHEMBL4764696 | 0.71 | TSHR (1.00) | LMNAKDM4EUSP2ALDH1A1MMP9 | |
| SCHEMBL576408 | 0.71 | TSHR (0.88) | LMNAKDM4EUSP2ALDH1A1MMP9 | |
| SCHEMBL10727268 | 0.71 | TSHR (0.60) | LMNAKDM4EUSP2ALDH1A1MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439932-A | Anticholesterol agents | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1995-08-08 | — | — | US | disclosed |
| US-5306728-A | Substituted amine derivatives having antihyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0448078-A2 | Substituted amine derivatives having anti-hyperlipemia activity | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1991-09-25 | — | — | EP | disclosed |